In this episode of the SBI podcast, host Dr. Karla Sepulveda welcomes Connie Lehman, MD, PhD to discuss how artificial intelligence is transforming breast cancer risk assessment. Dr. Lehman explains how AI-powered analysis of mammograms can identify women at elevated risk who may be missed by traditional risk models, paving the way for more personalized screening strategies. She also shares the story behind the development of the Mirai model and Clarity Breast, discusses recent NCCN guideline updates incorporating AI-based risk assessment, and explores the potential impact on screening recommendations, equity, and patient care.